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The following article was published in our article directory on November 1, 2010.
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US-made Small by Human Liver Stem Cells

Article Category: Business

Author Name: Amanda xzh

Scientists are trying to use stem cells in the laboratory to create a small human liver.

This success can be increased by creating a new liver for transplantation hope for, even though experts say it also requires a lot of years.

From the United States Wake Forest University Baptist Medical Center, a research group meeting in Boston presented their research results.

UK experts said it was "exciting development", but is not yet possible to determine whether foster healthy liver function.

The demand on the liver available for transplant far exceeds the number that can supply. In recent years, research has focused on finding the maintenance or use of cell technology will one day replace human organs methods recession. The basic components of these organs is stem cells, a kind of split under certain conditions, the formation of a variety of important human tissue cells. However, the use of stem cells to build a three-dimensional organs is a difficult task.

Researchers at Wake Forest University and other research groups in the world is used to the existing structure of the liver as a platform to generate new liver tissue.

According to this method, researchers used a detergent stripping of liver cells, liver cells, leaving only the collagen framework of support and the capillary network. Then, the new stem cells --- incomplete development of the liver cells and used to generate new blood vessel wall endothelial cells --- be gradually filled.

These add nutrients and oxygen with a variety of cultured cells in the bioreactor, a week later, the scientists observed that the liver appeared in the general structure of the phenomenon of cell development, and organ and even the small signs of some work.

Professor who led the study, said: "We study the possibility of excited about the show, it must be stressed that we are still in the initial stage, it must overcome many technical Zhangai to allow patients to benefit from the study. "

He said: "We not only need to figure out how to time a large number of liver cells cultured in order to manufacture enough of the liver patients, we also must determine if it is safe to use these organs."

British researchers believe the study results are encouraging. Imperial College London Professor Mark Withers said that these research results "encouraging."

He said: "The report shows that the researchers tackled the manufacture of artificial liver, one of the main obstacles, namely, the 'naturally occurring' liver structure in cultured normal human liver cells."

He said: "Obviously, these cells are well developed, but the next step is to prove that they can do like the work of normal human liver tissue."

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